The human body needs a small amount of cholesterol, but too much is bad for you. It clogs the arteries and increases your risk of heart disease, stroke and other problems.
Lifestyle changes, such as healthy eating and exercise, can help some people control their high cholesterol. But other people need medications to reduce their cholesterol levels.
Statins
Statins are tablets that are used to reduce the amount of cholesterol in your body. They can also reduce the risk of heart attacks and strokes. This is because they lower your LDL (low-density lipoprotein) cholesterol levels.
They can also raise your HDL (high-density lipoprotein) cholesterol, which is known as the “good” type of cholesterol. They work by slowing down the production of LDL-cholesterol in your liver.
You can take statins alone or with other medication to treat your cholesterol. Your doctor will help you choose the best combination to suit your needs and lifestyle.
If you’re taking a statin, your doctor will regularly check your blood cholesterol level and see whether it is improving. If your cholesterol level is not improving, they may suggest you try a different type of medication or increase your dose.
Your doctor will also discuss any dietary or other changes you can make to your lifestyle to reduce the level of cholesterol in your blood. Changing your diet and exercising can improve your cholesterol levels and reduce the need for a statin in some people.
Taking statins may be a lifelong commitment, depending on your age and health. But many people who have a high cholesterol level and are at high risk of a heart attack or stroke benefit from taking statins.
While there are some side effects to be aware of, they are usually mild and will go away as you adjust to the drug. They can include nausea, vomiting and aches in the muscles and joints.
You should speak with your doctor about these possible side effects before you start taking statins. Your doctor will recommend reducing the dosage of the statin, switching to a different medicine or stopping it altogether if you experience any unusual side effects.
Other medications you are taking or supplements you are taking can interact with statins, which can increase your chance of getting serious side effects. These can include kidney or liver problems.
Most people don’t experience these side effects and their doctors recommend continuing the treatment. You should also tell your doctor if you notice any changes in your muscle pain or weakness.
Resins
Resins (also called bile acid sequestrants) are tablets that bind to bile, a greenish fluid that your liver makes. They force your body to make more bile and use up cholesterol instead of absorbing it, lowering your LDL-cholesterol levels.
The two main resins are cholesterol kam karne ka tarika. They are taken orally in tablet form, usually with meals. They are not absorbed from the gastrointestinal tract, and their long-term use has been shown to be safe and effective.
Cholestyramine resins lower your cholesterol by binding to bile. It is important to note that resins do not directly lower triglycerides, but they may raise them slightly (about 5%).
These resins are often used as an adjunct to statin therapy when the statin is not working enough or if you have severe hypercholesterolemia. Taking resins and statins together increases your cholesterol-lowering effects.
They also increase the amount of HDL "good" cholesterol in your bloodstream, and decrease your liver's production of LDL "bad" cholesterol. These drugs can be a good option for patients who have trouble sticking with a cholesterol-lowering statin alone, but you should talk to your healthcare provider before taking them.
Because bile acid sequestrants can raise your triglycerides, you should make sure to take other medications that reduce triglycerides at least one hour before or four hours after taking them. It is important to keep track of your triglycerides and let your physician or pharmacist know if they rise.
Aside from bile acid resins, you can also take a niacin (nicotinic acid) drug and an omega-3 fatty acid medication to help reduce your triglycerides. Niacin, a B vitamin, may reduce your blood pressure and increase the production of HDL, or "good," cholesterol in your body.
Other lipid-lowering agents include fibrates, which work to reduce the production of cholesterol in the liver. Fibrates may also increase the level of HDL cholesterol, and they can be taken with statins.
The most effective and cost-effective way to reduce your cholesterol is to use a combination of a bile acid resin with a statin or other lipid-lowering medicine. The bile acid resins will be more cost-effective when used with a statin and HMG inhibitors, but low-dose resins are more effective on their own in most cases.
Niacin
Niacin, or vitamin B3, is a dietary supplement that you can take to help lower your cholesterol levels. It works by raising your HDL, or "good," cholesterol and lowering your LDL, or "bad," cholesterol. It also helps reduce triglycerides, which are the fats in your blood.
The best way to control your cholesterol is to follow a healthy diet and exercise regularly. However, for some people, this is not enough to keep their cholesterol levels down. These patients are often prescribed medicines to reduce their LDL cholesterol.
Doctors sometimes prescribe niacin in addition to other medications. These medicines may include rosuvastatin (Crestor, Ezallor), simvastatin (Flolipid, Zocor), fluvastatin (Lescol), atorvastatin (Lipitor) and pravastatin (Pravahi).
Some studies show that taking niacin supplements reduces your risk of developing high blood pressure or heart disease. The supplement can also reduce your risk of getting diabetes and Crohn's disease.
Another study showed that niacin can increase your HDL cholesterol and decrease your triglycerides. It can also lower your oxidized LDL cholesterol, the “sticky” type that can clog the walls of your arteries.
This is important because oxidized LDL cholesterol is more likely to cause a heart attack or stroke. You can get niacin from foods like liver, fish, meat, and whole grains.
You can also get niacin by taking it in pill form or by drinking a liquid that contains niacin. You can find these in health stores or at your doctor's office.
In some studies, niacin has been shown to improve levels of cholesterol and blood fats called triglycerides in HIV/AIDS patients with abnormal levels due to antiretroviral treatment. It also appears to improve cholesterol and triglyceride levels in patients with metabolic syndrome.
There are two forms of niacin available: immediate release and extended-release. Both have side effects, including flushing. Immediate-release niacin is usually taken twice a day with meals, while extended-release niacin is taken once a day.
It is a good idea to talk with your doctor cholesterol in urdu if you have a medical condition such as high blood pressure, diabetes, or Crohn's disease. Niacin can also affect the amount of insulin your body makes.
Omega-3 fatty acids
Omega-3 fatty acids, found in fish oils and certain foods, have been shown to benefit heart health. They reduce inflammation and blood clotting, lower cholesterol and triglycerides, and may help prevent diabetes and other chronic diseases.
They can be consumed in the form of supplements or fish, but there are also dietary sources such as flaxseeds, olive oil, and walnuts that are rich in fatty acids. It is important to note that dietary supplements should be used under the supervision of a physician.
There is limited evidence for the effectiveness of EPA and DHA in preventing or reversing cardiovascular disease (CVD). The REDUCE-IT study, which was a randomized, double-blind, placebo-controlled trial that enrolled 8,179 patients with CVD or type 2 diabetes with elevated triglycerides despite treatment with statins, was the first to demonstrate the efficacy of EPA.
This study showed that EPA and DHA can significantly reduce the risk of CVD in patients with type 2 diabetes and elevated triglycerides. This is especially true in patients with a history of coronary artery disease, who may be more susceptible to cardiovascular problems due to the presence of plaques in their arteries.
EPA and DHA are essential fatty acids that can be found in fish oils, eggs, nuts, flaxseeds, and other dietary sources. They are necessary for the body to produce hormones and cell membranes, and they also can improve mood.
In addition, EPA and DHA may help improve heart health by increasing HDL cholesterol. In fact, studies have shown that people who have high levels of fatty acids in their HDL are less likely to develop heart disease than those with low HDL.
Some omega-3 fatty acids also have anti-inflammatory properties that may help reduce the symptoms of conditions such as arthritis, asthma, ulcerative colitis, and rheumatoid arthritis. They also decrease blood pressure and fat deposits in the arteries, which helps reduce the risk of stroke.
The ALA, EPA, and DHA fatty acids can be found in a variety of foods such as fish, nuts, seeds, and cholesterol kam karne ka tarika in urdu. They are essential to a healthy diet and can be taken in tablet form or as an oil or capsule.
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